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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5f8712b67c27a560027ac9c48aff4ed6a07ebe8db77b3660755d63d0f135c7a' 
  AND token = 'y6nPu0NpKoLF+9/fIIMRQwnaaNEbKA7Gw5aYAA5cvtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}