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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433a6869bde6977a11ca558484065b9921ed7fe89c698cf12a892a3daa6ac756' 
  AND token = 'bAuVRJPLqgzvyZW80Tp+yu58bE2IdxtCUuLLFLb0MRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}