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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78124887425fce3e5f2e4700311ac788fa97fc73f4724e90153fe63bbe036a2' 
  AND token = '0PkxRJui69+/gbI+m4XLGmKIkNNMpClq9M4uJ+F4lOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}