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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaacc4c23894dcb09c091677b4e0a3df03b0716eabff6c77df37384cd2cba479' 
  AND token = 'PU+IB1garT8BpiLu8KzJcRIwix3k4upE4TOCHxRbDQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}