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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820ec1dcee812331b1653fd11a089c5b1db7f22a1c7f7775a2181a06881b25f8' 
  AND token = 'L60VFvx5y0isdgkXW/eyhhoxNZvQivHQWTLFkePyVWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}