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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ade8246c499120d084d2842cd046140db7e310e9d24a86aaa9c4e4bf4b60baf4' 
  AND token = '0ddqGuqlMEuyc6mbMx/mmL8bF5CWaCkqCC+54W0ZOnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}