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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aff0b4c0f186416a694a33bf9363f669fca013a46b95094646189ed1bb7543e' 
  AND token = 'sI0Wl+HqfwTiiERUC9K7dIBXU6kS+2VCaOvF0YKwB8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}