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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f75a4650c58ad94f1e6e479cbecff315047361d5736965218e3cd4905b719a' 
  AND token = 'PGT1xGGczFHoM54feO1XcTALq58GcD25UULjKmxa/9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}