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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff979b2c2b8e754a76a9fb77bca3784d2d4bfd596b6863af096cfcbfca81561' 
  AND token = 'bp8JwwDMss/b2GB4/nkmeQ7RNlT1InD3XiCmdS228NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}