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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ccd05da2e5ee63e7110a1eb4e2a2364ceb9d7b8086f9c388fae577017c20f6f' 
  AND token = 'tEUikEnhMuqxdiXgS4v6Rdiu2ib351oOLCMyB3BJa6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}