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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '020c28c5a848da332e82e2d43efba97ade2e02239e50bf4c7e6f749376cc045a' 
  AND token = 'fvw8h8mZ9S799/vk0a9/XaA1SFvrUOpYUUNlg6HoBDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}