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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59261408c3a8369b27337eedc3abbbe2c2fa0d28cd0a65f35de7607f7947032b' 
  AND token = 'b2tG75xLeKlABD1PweDkMbWI+TGTdU07GWr9FqNlrGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}