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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d300fe23896ff4042bcbde40954f79f64a4ad6c54e62bc5f89496c35d5ce232' 
  AND token = 'GWuYYAFM5+nS+38j016Qg4+h+8ZmAtE+8jCpKpVY8+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}