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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '933d83a975f0185b327b60727e4ba699156a50ffa258c5a9223150fd6ee79a19' 
  AND token = 'VD0/JhICpbY51qqAjisziebur3dMU7QKL0RbnOI8Oc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}