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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb6a4117fa6cdac33be72d6c8f1d727c1059144d938ae27e5a8bdeddacf2286' 
  AND token = 'VutMZAOhU57aJkLPIbg1VW5aBL2o1NknsIShArUb+vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}