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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d9fbf3e0d120529cf45c6fb9487e2ef8529fad941a8ad6624d324759f41b21' 
  AND token = 'OeX4vjrlVHlf/EkwYSRzwcEYfcf88Bwtr2R3V1+pdoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}