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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81d2265814ff488c930a9f5853a76b12e328050c5db67ef21b9181bf8be9b3b' 
  AND token = '/ImfWke02GV0BQNdqr9bqE/nsTKA3fB9lIBRykDMf4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}