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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d9c95317ae05466488c3f63a3a217ebe0f88e936815a34842e233b298ce51f' 
  AND token = 'Z48Ij2E5D6cmcUk5fp+Kcc28D7jR5L98jHRkxcIdWcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}