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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afca326b2c29972b7e6815425b2f1960e05316d5e95f859be0a608d3ebbb7bad' 
  AND token = 'Sva/Km8Whf+2cS2ZkaJU3uNKiBNCrAEQXH1Uv1yWCdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}