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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250b498e767437a0c4476e5abd35bffb09b60af75f32e78103d22d669cad09a5' 
  AND token = 's8sjHH5CBHA8m1z06BueXyWDtODcLmqOxu0Lx7ocTM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}