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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c568233668ab92c0334a296b55ff9bf72bd04e117dbf35f85d8f78155d9a5213' 
  AND token = 'lQaA5dWU7BE/4adwpZEC/+5rPWSIXw3HwA7PAgxYt84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}