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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fded0e0410939ca287053e53f4d3da706901dfbc335929af0a07c2674dc6469' 
  AND token = 'YYBH31Mwpjvg0oI82w6D5kDzzSwMP/Db82S3Tj2j4gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}