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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5448462981c6bed16c3dc948969f676c9890162138a1c1e820aeb96003757bd' 
  AND token = 'D4Z+MCN8AvYe9YCmYNO+08rN0YkT34/WkGPbPFvrHEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}