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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07ef4e75c9fa9368d43ee9c3635152d6838af518f1ec5da30aa8af68114bf906' 
  AND token = 'giKDvN7j+WbKmUlbD+drfafIKdohvz0N1BrXQZjMawk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}