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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65549c28f531d19d2b7a041a34abbb5e982f232d61ff857f3c00ec9cc6bcfc7a' 
  AND token = 'GO6ZBvo9T6T3WO9unS9tbUown1Xd/NLLct+6yHEpRFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}