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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7602ab716c75e54271f024343db43c408fdd3e8ba89f3f8a6c04434df0ae27d5' 
  AND token = 'RqJDMd6gLR/TAQABHE/q9Tmf38PFleL7Mm8uPu5wbUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}