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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ad4fc01c241f959f221127cc5e75e83d72efd069a312183faa14080eeccbc1' 
  AND token = 'iw4QVRhKb25pXXz6D2QdUlLONpeTUXl9aj9Rc2sMOLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}