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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdc6dd5fd9e42cf4fa7af33b9fee1cca3fd05b463a6b226b800868487819145e' 
  AND token = 'bDBF6l3g220OFEGL2vZMCaYc8tusP5ALgdeOs1+i7GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}