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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acab44bf05d1d5b617e2375d3be4295d0e60d9984e86a189d4994249c3de9fd' 
  AND token = 'DyGP8muS2AeflKWdaLVZSbrYSOn3tgN1VoqWIyN+Rz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}