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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8926eee2c6ac8dfa0322d30b468f24e833e2d801a3737d0f2df53e1fc8f91a' 
  AND token = 'a887GimIJk+Di1kYxlEnrRMf8BGLseefDiWntZ69R+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}