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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca1cc16b7de73d9fb5c70384460b28604e22cbe8c22b26d0e26f83b96eb43fb' 
  AND token = '+e2aA8tsBAW8BwP2OWCXaP5tvq2MyetzBzszhjEM8Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}