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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e11a95fdbef147d7d61f707b678662171e66c743e71cf0874142234942ba24b' 
  AND token = 'PmKGtW/y4vT5EMUsdYtz4le5OUwoC45JIQdFaLXiiPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}