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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e01f364a42a16fe2532853f8198f2674e05db783af9fa433950c5228b1789ad' 
  AND token = 'ADa3ckAd2Lsr+eWxo6v+JT7K67B3RaLoRQoskwMkJfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}