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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5910312159a7c34b741f78846e5d197a3aa7260e14eaafd9bd00ae0ec2efbd65' 
  AND token = 'rVBVc7Xg8KCemSTZuaW06eNkdFBlgYf+mA9YDZr0P0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}