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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c50b824da6987704553b9815a69e82b6a49f803bfe85be81b033437ec32b579' 
  AND token = 'XqkIa4FuQ7/ckPaj10DUq4CyQvyyFV+SB+so5RSU3as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}