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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e14b7c37b7b87ad50e29051730019024538c9ad547f9f8a105ad767b4eb01a1' 
  AND token = '0VbPqpH8otd8nZW9UTVpTLwAx2bwjwwmRdhdNs5Wi/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}