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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea0316e51739a8bd9da64c77731bd615880854930d0f15deb461deafeba15b51' 
  AND token = 'ETM3E+12Vg/ta6Vfq8v0M4jTG09aFq90SIUZC4TEEAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}