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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e21c01e026c3e6430e3e585d6fd7a83991f47d88c1834a817850ed59a09b39' 
  AND token = 'XCfWX6C/UsSBOTS6FFXjCwdKGLQkWwiS+x6XAroEWYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}