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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2165c59f3903f83e09e52f5f30762b47dc766a7ac51ae24052a7ffc477dfc3ca' 
  AND token = '4gmIQCvvFcCCywABdpFbAX0Nvd4pCdC5L6Jf/vJf+PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}