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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80f7167b53bc6bd7ad89d8063c30003dad4ed7a03b740b70b31658e629fbb39' 
  AND token = 'jNl7rf0rN5pNVCl7x3Pv/sCoyLA57vgHEyhko97REZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}