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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db80ff44bedb24f78e0b5cc93084feebb78aa5b49497f02aa8764567dc4e73d7' 
  AND token = 'rJsQkM8W+gRJ5nWi1NlWAKseQlqYd/ItrqdB6sC+pyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}