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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af60d6c8608cf502c3298efe96c039929545b8e67c87ced22798d84f0ca54377' 
  AND token = 'XPY9rdozSlNr2Gbw3tj/T/XaNwvUNPe2YHN/+GimSQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}