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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2cffeae28d1678f30b591dd853773ad10ab76db10825b56535a4074e1ecc411' 
  AND token = '+eIkcFSqsN7mwX9dIz0sW3EW8he2NlBrEtdY9oYRlvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}