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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb9c67ab928267893914d0ea2b6c28ac292fa6b75b0e195a0bdec5f2e5c9778' 
  AND token = 'uJek25xNPcyR+LE85+0PmsOtCAl/Qt7rKNjTiL4rnBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}