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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0543c742e6fbf3d15f8cce55d1bcbdd4f6746e1f01b8f7af43a6218773524ffe' 
  AND token = 'lu9PD6lR30GQfSsmCTlqGL0t1bI4PkTU8BZ2rNkD/Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}