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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb01e90021cbbbfac20b8129d2a4727a34034fde0949a26dd2d4f6b5724e2c0' 
  AND token = 'AvkxuBPz+Cjs+FvK13PkX6HBPTBapWhJrFDaCVkkvxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}