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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f250cf3729cb8f30b4ad3bccfb5a0b1c8a3f15fe753f44e9e05c6a7ecedbf790' 
  AND token = 'MgwiGDnZarOXxa3Cs2wV3BPuEktIhlLrGdBd3YupTXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}