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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2c5a807100c0f00c00c222cb5ef9def7d5725e17b73d6f68b0106e0f7d1aef' 
  AND token = 'DcyszKEdkY7VQxiRYFhwwv+tUBdYgHb0NoX0hHy/vGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}