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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c17b995932bea15df7da32cf82af4246b760078c96b36b0da258037004c8a73' 
  AND token = '487dy/FY4TdTsNc6Y1Q+IXscknJK91JS6oiM4CmaCUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}