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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce661374708209cd1e5a0f1a12f668890ad766989827782b845b522595aa0458' 
  AND token = 'YTesvlERkio3TK2R6Ag6HSuNeA7IVl56V/pRSPwkvpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}